Thursday, February 12, 2009

Fraud, The MMR Vaccine, and Autism

In February 1998, a paper was published in The Lancet that turned the world upside down for the parents of kids with autism. The study was extremely small, consisting of only 12 kids. In that study the researchers claimed that eight of the 12 kids' autism could be attributed directly to being vaccinated with the MMR vaccine. This set off a firestorm around the world. Parents who had been grasping for any explanation or reason for their child's affliction suddenly had a scapegoat. "It was that damned vaccine!" everyone said. It has been eleven years, almost to the day, when that study was published. Since then, tens of thousands of kids have not been vaccinated against Measles, Mumps, or Rubella because their parents were terrified that doing so would destroy their child's mind. But now the truth is revealed. The research was bogus. The findings were fabricated.

H/T Clayton Cramer

3 Comments:

Blogger Jean said...

I heard about this on the radio. I have no idea why there has been an explosion of autism in this country, but it's horrifying to think this kind of malfeasance in the medical/scientific community has exposed children to multiple diseases through fear mongering. Just horrible.

February 15, 2009 5:36 AM  
Blogger Rorschach said...

By and large the "explosion" you cite is actually just better diagnosis and an expansion of what qualified as "autism" which encompasses far more kids than it used to.

February 15, 2009 9:07 AM  
Anonymous Anonymous said...

See the following theory:
The ‘theory of mind’ (ToM) hypothesis of autism. Tom is an hypothesis first published in 1985.
Other articles ask what caused the autism epidemic?
The CDC studies say it is not MMR or Thimerosal. Other hypotheses have included autoimmune diseases, etc.

Data:
Individuals with Disabilities Education Act (IDEA) Data website:
http://www.ideadata.org/PartBChildCount.asp
Pregnancy Risk Assessment Monitoring System (PRAMS) sleep position data:
http://www.cdc.gov/prams/2002PRAMSSurvReport/MultiStateExhibits/Multistates16.htm
Centers for Disease Control (CDC) Birth Data:
http://www.cdc.gov/nchs/births.htm
2006 Median Income Data: - U.S. Department of Housing and Urban Development
NOTICE PDR-2006-01

Autism Spectrum Disorders, Asperger's Syndrome, and Pervasive Developmental Disorders - Not Otherwise specified (PDD-NOS)
Gastrointestinal Disorders also known as GER is a common comorbidity
Autism patients tend to have minicolumn abnormalities and increased amounts of white matter
Casanova MF, van Kooten IA, Switala AE, Ven Engeland H, Heinsen H, Steinbusch HW, Hof PR, Trippe J, Stone J, Schmitz C. Minicolumnar abnormalities in autism. Acta Neuropathol. 2006 Sep; 112(3); 287-303.
Mostofsky SH, Burgess MP, Larson JCG. Increased motor cortex white matter volume predicts motor impairment in autism. Brain (2007), 130, 2117-2122

Maternal smoking decreased significantly between 1990 and 2002
Infant suffocation deaths increased 14% per year on average between 1996 and 2004
Centers for Disease Control. Smoking & Tobacco Use - Morbidity and Mortality Weekly Reports (MMWRs) – Smoking During Pregnancy – United States, 1990-2002 – October 7, 2004 / Vol. 53/ No. 39 http://www.cdc.gov/tobacco/data_statistics/MMWR/2004/mm5339_highlights.htm
Shapiro-Mendoza CK, Kimball M, Tomashek KM, Anderson RN, Blanding S.US Infant Mortality Trends Attributable to Accidental Suffocation and Strangulation in Bed From 1984 Through 2004: Are Rates Increasing? Pediatrics 2009;123;533-539

Here is a good article on diagnosing this:
Filipek P, Accardo P, Ashwal S, Baranek G, Cook E, Dawson G, Gordon B, Gravel J, Johnson C, Kallen R, Levy S, Minshew N, Ozonoff S, Prizant B, Rapin I, Rogers S, Stone W, Teplin S, Tuchman R, Volkmar F. Practice parameter: Screening and diagnosis of autism Report of the Quality Standards Subcommittee of the American Academy of Neurology and the Child Neurology Society NEUROLOGY 2000;55:468–479 http://internet.dscc.uic.edu/forms/medicalhome/AutismRef.pdf

Also,
SIDS, Autism, Autism Spectrum Disorder, Plagiocephaly, etc. are all
conditions that the medical profession is trying to treat.
The SIDS back sleep (Supine) sleep recommendations began in 1992
The SIDS "Back to Sleep" campaign began in 1994.
In 1996 the AAP SIDS Task Force, led by Dr. John Kattwinkel recommended the supine sleep position and not the side(lateral) or front(prone).
THe Netherlands began their SIDS Back to Sleep Campaign in 1987.
Sleep is necessary for memory consolidation, declarative learning, and procedural learning.


The following are useful articles which discuss many of these issues indepth:
American Academy of Pediatrics Task Force on Infant Positioning and SIDS. Positioning and SIDS. Pediatrics. 1992;89:1120-1126
Hogberg U, Bergstrom E. Suffocated Prone: The Iatrogenic Tragedy of SIDS. American Journal of Public Health. 2000;90:527-531
National Infant Sleep Position Household Survey. Summary Data. updated: 10/16/08 Website: http://dccwww.bumc.bu.edu/ChimeNisp/NISP_Data.asp
Kattwinkel J, Hauck F.R., Moon R.Y., Malloy M and Willinger M Infant Death Syndrome: In Reply, Bed Sharing With Unimpaired Parents Is Not an Important Risk for Sudden. Pediatrics 2006;117;994-996
Buzsáki, G. 1989. Two-stage model of memory trace formation: A role for “noisy” brain states. Neuroscience 31: 551–570.
Hasselmo, M.E. 1999. Neuromodulation: Acetylcholine and memory consolidation. Trends Cogn. Sci. 3: 351–359.
Wierzynski DM, Lubenov EV, Gu M, Siapas AG. State-Dependent Spike-Timing Relationships between Hippocampal and Prefrontal Circuits during Sleep. Neuron 61, 587-596, February 26, 2009
Walker MP, Stickgold R. Sleep, Memory, and Plasticity. Annu. Rev. Psychol. 2006. 57: 139-66
Gais S, Born J. Declarative memory consolidation: Mechanisms acting during human sleep. Learn Mem. 2004 Nov-Dec; 11(6): 679-685
Davis BE, Moon RY, Sachs HC, Ottolini MC. Effects of sleep position on infant motor development. Pediatrics. 1998 Nov; 102(5):1135-40.
Skadberg BT, Markestad T. Consequences of Getting the Head Covered During Sleep in Infancy. Pediatrics 1997;100;e6
AJ Williams, RD Jitendra, JB Phillips, Y Lin, T McCabe, FC Tortella. Neuroprotective Efficacy and Therapeutic Window of the High-Affinity N-Methyl-D-aspartate Antagonist Conantokin-G: In Vitro (Primary Cerebellar Neurons) and In Vivo (Rat Model of Transient Focal Brain Ischemia) Studies1
Stradling JR, Thomas G, Warley AR, Williams P, Freeland A. Effect of adenotonsillectomy on nocturnal hypoxaemia, sleep disturbance, and symptoms in snoring children. Lancet. 1990;335 :249 –253

May 12, 2009 9:58 PM  

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